human FLJ42280 Adenovirus
This is an Adenovirus expressing Human CDKL5.
ADV-209137
Ad-h-FLJ42280
Ready-to-use Adenovirus expressing Human C7orf76 (chromosome 7 open reading frame 76). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Gene ID
401388
Gene Name (Vector)
chromosome 7 open reading frame 76
Gene Symbol
C7orf76
ORF Size (aa)
357
ORF Size (bp)
357 bp
RefSeq ID
NM_001201451
RefSeq Synonyms
NM_001201451, NM_001201450, BC171740, BC140736,
Species
human
UniGene ID
Hs.534805
Related Citations
- Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons. M Loi, etc, (2020), Molecular Neurobiology
- CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling. C Fuchs, etc, (2019), Brain Pathology
- Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder. C Fuchs, etc, (2019), Neuropharmacology
- HDAC4: A Key Factor Underlying Brain Developmental Alterations in CDKL5 Disorder. S Trazzi, etc, (2016), Human Molecular Genetics
- Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3ß signaling. Claudia Fuchs, etc, (2014), Neurobiology of Disease
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.