human FIG4 Adenovirus

Name
Ad-h-FIG4

Cat No
ADV-209027

Availability
4-5 weeks

This is an Adenovirus expressing Human FIG4.

ADV-209027

Ad-h-FIG4

Ready-to-use Adenovirus expressing Human FIG4 (FIG4 phosphoinositide 5-phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ALS11; BTOP; CMT4J; dJ249I4.1; KIAA0274; SAC3; YVS

Description (Vector)

FIG4 belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

Gene ID

9896

Gene Name (Vector)

FIG4 phosphoinositide 5-phosphatase

Gene Symbol

FIG4

HGNC ID

HGNC:16873

ORF Size (aa)

2724

ORF Size (bp)

2724 bp

RefSeq ID

NM_014845

RefSeq Synonyms

NM_014845, BC041338,

Species

human

UniGene ID

Hs.529959

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.