human E2F3 Adenovirus
This is an Adenovirus expressing Human E2F3.
ADV-207493
Ad-h-E2F3
Ready-to-use Adenovirus expressing Human E2F3 (E2F transcription factor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E2F-3
Description (Vector)
E2F3 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1871
Gene Name (Vector)
E2F transcription factor 3
Gene Symbol
E2F3
HGNC ID
HGNC:3115
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_001949
RefSeq Synonyms
NM_001949, NM_001243076, BC172526, BC156367, BC016847,
Species
human
UniGene ID
Hs.703174
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.