human CUL4B Adenovirus
This is an Adenovirus expressing Human CUL4B.
ADV-206302
Ad-h-CUL4B
Ready-to-use Adenovirus expressing Human CUL4B (cullin 4B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CUL-4B; cullin-4B; MRXHF2; MRXS15; MRXSC; SFM2
Description (eCommerce)
Cullin-4B is a member of the cullin family. Cullin-4B forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. Cullin-4B interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E [taken from NCBI Entrez Gene (Gene ID: 8450)].
Description (Vector)
CUL4B is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
8450
Gene Name (eCommerce)
cullin 4B
Gene Name (Vector)
cullin 4B
Gene Symbol
CUL4B
HGNC ID
HGNC:2555
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2742
ORF Size (bp)
2742 bp
Protein Name (eCommerce)
Cullin-4B
RefSeq ID
NM_003588
RefSeq Synonyms
NM_003588, NM_001330624, NM_001079872, BC036216,
Research Areas
Cell Cycle,DNA Damage/Repair,Immunology,Metabolism/Metabolic Process,Neurobiology,Ubiquitination
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,immunology,metabolism,neurobiology
Species
human
Target Sentence
Cullin-4B is a member of the cullin family. Cullin-4B forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. Cullin-4B interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E [taken from NCBI Entrez Gene (Gene ID: 8450)].
UniGene ID
Hs.102914
UniProt ID (eCommerce)
Q13620
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.