human CTNND2 Adenovirus

Name
Ad-h-CTNND2

Cat No
ADV-206253

Availability
4-5 weeks

This is an Adenovirus expressing Human CTNND2.

ADV-206253

Ad-h-CTNND2

Ready-to-use Adenovirus expressing Human CTNND2 (catenin delta 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GT24; NPRAP

Description (Vector)

CTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. CTNND2 is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. CTNND2 resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.

Gene ID

1501

Gene Name (Vector)

catenin delta 2

Gene Symbol

CTNND2

HGNC ID

HGNC:2516

ORF Size (aa)

3675

ORF Size (bp)

3675 bp

RefSeq ID

NM_001332

RefSeq Synonyms

NM_001332, NM_001288717, NM_001288716, NM_001288715, BC111837,

Species

human

UniGene ID

Hs.314543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.