human CRYGA Adenovirus
This is an Adenovirus expressing Human LKAAEAR1.
ADV-206064
Ad-h-CRYGA
Ready-to-use Adenovirus expressing Human CRYGA (crystallin gamma A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CRY-g-A; CRYG1; CRYG5
Description (Vector)
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
Gene ID
1418
Gene Name (Vector)
crystallin gamma A
Gene Symbol
CRYGA
HGNC ID
HGNC:2408
ORF Size (aa)
318
RefSeq ID
NM_014617
RefSeq Synonyms
NM_014617, BC114456,
Species
human
UniGene ID
Hs.122566
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.