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human CREB3 Adenovirus

Name 
Ad-h-CREB3
Cat No 
ADV-205973
Availability
4-5 weeks

This is an Adenovirus expressing Human CREB3.

ADV-205973
Ad-h-CREB3

Ready-to-use Adenovirus expressing Human CREB3 (cAMP responsive element binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LUMAN; LZIP; sLZIP
Description (Vector)
CREB3 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
Gene ID
10488
Gene Name (Vector)
cAMP responsive element binding protein 3
Gene Symbol
CREB3
HGNC ID
HGNC:2347
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_006368
RefSeq Synonyms
NM_006368, BC010158, BC009402,
Species
human
UniGene ID
Hs.522110

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.