human CLIP2 Adenovirus

Name 
Ad-h-CLIP2
Cat No 
ADV-205461
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CLIP2.

ADV-205461
Ad-h-CLIP2

Ready-to-use Adenovirus expressing Human CLIP2 (CAP-Gly domain containing linker protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAP-Gly domain-containing linker protein 2; CLIP; CLIP-115; CYLN2; cytoplasmic linker 2; cytoplasmic linker protein 115; cytoplasmic linker protein 2; testicular tissue protein Li 40; WBSCR3; WBSCR4; williams-Beuren syndrome chromosomal region 3 protein; williams-Beuren syndrome chromosomal region 4 protein; Williams-Beuren syndrome chromosome region 3; Williams-Beuren syndrome chromosome region 4; WSCR3; WSCR4
Description (eCommerce)
CLIP-115 (cytoplasmic linker protein 115) was found to associate with both microtubules and an organelle called the dendritic lamellar body. The CLIP-115 protein is encoded by the CLIP2 gene which is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23 [taken from NCBI Entrez Gene (Gene ID: 7461)].
Description (Vector)
CLIP2 belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
Gene ID
7461
Gene Name (eCommerce)
CAP-Gly domain containing linker protein 2
Gene Name (Vector)
CAP-Gly domain containing linker protein 2
Gene Symbol
CLIP2
HGNC ID
HGNC:2586
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3036
ORF Size (bp)
3036 bp
Protein Name (eCommerce)
CAP-Gly domain-containing linker protein 2
RefSeq ID
NM_003388
RefSeq Synonyms
NM_032421, NM_003388, BC150332, BC148702, BC140369,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Neurobiology
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,neurobiology
Species
human
Target Sentence
CLIP-115 (cytoplasmic linker protein 115) was found to associate with both microtubules and an organelle called the dendritic lamellar body. The CLIP-115 protein is encoded by the CLIP2 gene which is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23 [taken from NCBI Entrez Gene (Gene ID: 7461)].
UniGene ID
Hs.647018
UniProt ID (eCommerce)
Q9UDT6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.