human CD3D Adenovirus

Name 
Ad-h-CD3D
Cat No 
ADV-204645
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CD3D.

ADV-204645
Ad-h-CD3D

Ready-to-use Adenovirus expressing Human CD3D (CD3d molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD antigen CD3d; CD3 antigen, delta subunit; CD3 delta; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; IMD19; OKT3, delta chain; T3D; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain
Description (eCommerce)
The protein encoded for by CD3D, T-cell surface glycoprotein CD3 delta chain, is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. CD3 delta chain, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells [taken from NCBI Entrez Gene (Gene ID: 915)].
Description (Vector)
CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Gene ID
915
Gene Name (eCommerce)
CD3d molecule
Gene Name (Vector)
CD3d molecule
Gene Symbol
CD3D
HGNC ID
HGNC:1673
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
516
ORF Size (bp)
516 bp
Protein Name (eCommerce)
T-cell surface glycoprotein CD3 delta chain
RefSeq ID
NM_000732
RefSeq Synonyms
NM_001040651, NM_000732, BC070321, BC039035,
Research Areas
Apoptosis,Host-Virus Interactions,Immunology,Interleukin Signaling,NF-kB Signaling,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,infectious_disease,immunology,signal_transduction
Species
human
Target Sentence
The protein encoded for by CD3D, T-cell surface glycoprotein CD3 delta chain, is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. CD3 delta chain, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells [taken from NCBI Entrez Gene (Gene ID: 915)].
UniGene ID
Hs.504048
UniProt ID (eCommerce)
P04234

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.