human CAPN7 Adenovirus

Name 
Ad-h-CAPN7
Cat No 
ADV-204051
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CAPN7.

ADV-204051
Ad-h-CAPN7

Ready-to-use Adenovirus expressing Human CAPN7 (calpain 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
calpain like protease; CALPAIN7; calpain-7; homolog of Aspergillus Nidulans PALB; palB homolog; PALBH
Description (eCommerce)
CAPN7 is part of a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. [taken from NCBI Entrez Gene (Gene ID: 23473)].
Description (Vector)
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.
Gene ID
23473
Gene Name (eCommerce)
calpain 7
Gene Name (Vector)
calpain 7
Gene Symbol
CAPN7
HGNC ID
HGNC:1484
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2442
ORF Size (bp)
2442 bp
Protein Name (eCommerce)
Calpain-7
RefSeq ID
NM_014296
RefSeq Synonyms
NM_014296, BC056202,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
CAPN7 is part of a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. [taken from NCBI Entrez Gene (Gene ID: 23473)].
UniGene ID
Hs.631920
UniProt ID (eCommerce)
Q9Y6W3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.