human C2ORF3 Adenovirus

Name 
Ad-h-C2ORF3
Cat No 
ADV-203298
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human C2ORF3.

ADV-203298
Ad-h-C2ORF3

Ready-to-use Adenovirus expressing Human GCFC2 (GC-rich sequence DNA-binding factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C2orf3; DNABF; GC binding factor; GC bindng factor; GCF; GC-rich sequence DNA-binding factor; GC-rich sequence DNA-binding factor 2; TCF9; TCF-9; Transcription factor 9; transcription factor 9 (binds GC-rich sequences)
Description (eCommerce)
GCF (GC-rich sequence DNA-binding factor) was identified as a factor that bound to GC-rich sequences and repressed transcription of the epidermal growth factor (EGF) receptor, beta-actin, and calcium-dependent protease promoters. Since its initial cloning and characterization, GCF has been observed to be a transcriptional repressor of several growth factor/receptor genes.
Description (Vector)
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Gene ID
6936
Gene Name (eCommerce)
GC-rich sequence DNA-binding factor 2
Gene Name (Vector)
GC-rich sequence DNA-binding factor 2
Gene Symbol
GCFC2
HGNC ID
HGNC:1317
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2346
ORF Size (bp)
2346 bp
Protein Name (eCommerce)
GC-rich sequence DNA-binding factor 2
RefSeq ID
NM_003203
RefSeq Synonyms
NM_003203, NM_001201335, NM_001201334, BC064559, BC000853,
Research Areas
mRNA Processing,mRNA Splicing,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
GCF (GC-rich sequence DNA-binding factor) was identified as a factor that bound to GC-rich sequences and repressed transcription of the epidermal growth factor (EGF) receptor, beta-actin, and calcium-dependent protease promoters. Since its initial cloning and characterization, GCF has been observed to be a transcriptional repressor of several growth factor/receptor genes.
UniGene ID
Hs.303808
UniProt ID (eCommerce)
P16383

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.