human BUB3 Adenovirus

Name 
Ad-h-BUB3
Cat No 
ADV-202357
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ARFIP1.

ADV-202357
Ad-h-BUB3

Ready-to-use Adenovirus expressing Human BUB3 (BUB3, mitotic checkpoint protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BUB3 budding uninhibited by benzimidazoles 3 homolog; BUB3L; budding uninhibited by benomyl; budding uninhibited by benzimidazoles 3 homolog; hBUB3; mitotic checkpoint component; mitotic checkpoint protein BUB3; testicular tissue protein Li 27
Description (eCommerce)
Bub3 is an adaptor protein and component of the spindle checkpoint machinery. Bub3 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. Bub3 forms a constitutive complex with Bub1. Bub3 has been demonstrated to also function as a transcriptional repressor in association with Cdc20 and histone deacetylases.
Description (Vector)
BUB3 encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
9184
Gene Name (eCommerce)
BUB3, mitotic checkpoint protein
Gene Name (Vector)
BUB3, mitotic checkpoint protein
Gene Symbol
BUB3
HGNC ID
HGNC:1151
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
987
ORF Size (bp)
987 bp
Protein Name (eCommerce)
Mitotic checkpoint protein BUB3
RefSeq ID
NM_004725
RefSeq Synonyms
NM_004725, NM_001007793, BC022438, BC005138,
Research Areas
Aging,Cell Cycle,Cell Division,Host-Virus Interactions,Meiosis
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,infectious_disease
Species
human
Target Sentence
Bub3 is an adaptor protein and component of the spindle checkpoint machinery. Bub3 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. Bub3 forms a constitutive complex with Bub1. Bub3 has been demonstrated to also function as a transcriptional repressor in association with Cdc20 and histone deacetylases.
UniGene ID
Hs.418533
UniProt ID (eCommerce)
O43684

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.