Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human BRWD2 Adenovirus

Name 
Ad-h-BRWD2
Cat No 
ADV-202292
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human BRWD2.

ADV-202292
Ad-h-BRWD2

Ready-to-use Adenovirus expressing Human WDR11 (WD repeat domain 11). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bromodomain and WD repeat-containing protein 2; BRWD2; DR11; HH14; sensitization to ricin complex subunit 1; SRI1; WD repeat domain 15; WD repeat-containing protein 11; WD repeat-containing protein 15; WDR15
Description (eCommerce)
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The WDR11 gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.[taken from NCBI Entrez Gene (GeneID: 55717)].
Description (Vector)
WDR11 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR11 is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Gene ID
55717
Gene Name (eCommerce)
WD repeat domain 11
Gene Name (Vector)
WD repeat domain 11
Gene Symbol
WDR11
HGNC ID
HGNC:13831
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3675
ORF Size (bp)
3675 bp
Protein Name (eCommerce)
WD repeat-containing protein 11
RefSeq ID
NM_018117
RefSeq Synonyms
NM_018117, BC071564, BC040469,
Research Areas
Cancer,Immunology,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,immunology
Species
human
Target Sentence
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The WDR11 gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.[taken from NCBI Entrez Gene (GeneID: 55717)].
UniGene ID
Hs.144447
UniProt ID (eCommerce)
Q9BZH6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.