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human BCAM Adenovirus

Name 
Ad-h-BCAM
Cat No 
ADV-202004
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human BCAM.

ADV-202004
Ad-h-BCAM

Ready-to-use Adenovirus expressing Human BCAM (basal cell adhesion molecule (Lutheran blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AU; CD239; LU; MSK19
Description (Vector)
BCAM encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
4059
Gene Name (Vector)
basal cell adhesion molecule (Lutheran blood group)
Gene Symbol
BCAM
HGNC ID
HGNC:6722
ORF Size (aa)
1887
ORF Size (bp)
1887 bp
RefSeq ID
NM_005581
RefSeq Synonyms
NM_005581, NM_001013257, BC050450,
Species
human
UniGene ID
Hs.625725

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.