human ATP6V1B2 Adenovirus
This is an Adenovirus expressing Human ATP6V1B2.
ADV-201758
Ad-h-ATP6V1B2
Ready-to-use Adenovirus expressing Human ATP6V1B2 (ATPase H+ transporting V1 subunit B2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATP6B1B2; ATP6B2; DOOD; HO57; VATB; Vma2; VPP3; ZLS2
Description (Vector)
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Gene ID
526
Gene Name (Vector)
ATPase H+ transporting V1 subunit B2
Gene Symbol
ATP6V1B2
HGNC ID
HGNC:854
ORF Size (aa)
1536
ORF Size (bp)
1536 bp
RefSeq ID
NM_001693
RefSeq Synonyms
NM_001693, BC030640, BC003100,
Species
human
UniGene ID
Hs.295917
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.