human ARF6 Adenovirus

Name 
Ad-h-ARF6
Cat No 
ADV-201278
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ARF6.

ADV-201278
Ad-h-ARF6

Ready-to-use Adenovirus expressing Human ARF6 (ADP ribosylation factor 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ADP-ribosylation factor 6
Description (eCommerce)
ADP-ribosylation factor 6 (ARF6) is a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and plays a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling [taken from NCBI Entrez Gene (Gene ID: 382)].
Description (Vector)
ARF6 encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
Gene ID
382
Gene Name (eCommerce)
ADP ribosylation factor 6
Gene Name (Vector)
ADP ribosylation factor 6
Gene Symbol
ARF6
HGNC ID
HGNC:659
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
528
ORF Size (bp)
528 bp
Protein Name (eCommerce)
ADP-ribosylation factor 6
RefSeq ID
NM_001663
RefSeq Synonyms
NM_001663, BC008918,
Research Areas
Apoptosis,Cancer,Cell Cycle,Cell Division,Cytoskeleton,EGFR Signaling,Golgi Apparatus,HGF Signaling,Immunology,Insulin Signaling,Lung Cancer,Neurobiology,Neurodevelopment,Neurogenesis,Signal Transduction,Translational Control
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
ADP-ribosylation factor 6 (ARF6) is a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and plays a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling [taken from NCBI Entrez Gene (Gene ID: 382)].
UniGene ID
Hs.682124
UniProt ID (eCommerce)
P62330

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.