human APOA2 Adenovirus

Name 
Ad-h-APOA2
Cat No 
ADV-201168
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AHSA2.

ADV-201168
Ad-h-APOA2

Ready-to-use Adenovirus expressing Human APOA2 (apolipoprotein A2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
apoAII; Apo-AII; ApoA-II; Apolipoprotein A2; apolipoprotein A-II
Description (eCommerce)
Apo AII comprises 25% of HDL. It exists in human plasma as a dimer of 2 identical chains of 77 amino acid residues, joined by disulfide. The molecular weight is reported to be 8.7 kDa for a single chain (Brewer et al., 1972).Studies on mouse reported that apo AII may be proatherogenic (Warden et al., 1993); however, case-control study in the large European Prospective Investigation demonstrated that plasma Apo AII concentrations were strongly inversely correlated with CHD events. (Birjmohun et al., 2007)
Description (Vector)
APOA2 encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
Gene ID
336
Gene Name (eCommerce)
apolipoprotein A2
Gene Name (Vector)
apolipoprotein A2
Gene Symbol
APOA2
HGNC ID
HGNC:601
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
303
ORF Size (bp)
303 bp
Protein Name (eCommerce)
Apolipoprotein A-II
RefSeq ID
NM_001643
RefSeq Synonyms
NM_001643, BC005282,
Research Areas
Cardiovascular
Research Areas (Faceted)
cardiovascular
Species
human
Target Sentence
Apo AII comprises 25% of HDL. It exists in human plasma as a dimer of 2 identical chains of 77 amino acid residues, joined by disulfide. The molecular weight is reported to be 8.7 kDa for a single chain (Brewer et al., 1972).Studies on mouse reported that apo AII may be proatherogenic (Warden et al., 1993); however, case-control study in the large European Prospective Investigation demonstrated that plasma Apo AII concentrations were strongly inversely correlated with CHD events. (Birjmohun et al., 2007)
UniGene ID
Hs.237658
UniProt ID (eCommerce)
P02652

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.