human APEX2 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-201142
Availability:
3-5 weeks
Name:
Ad-h-APEX2
This is an Adenovirus expressing Human APEX2.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- APEX2
- Gene Name
- apurinic/apyrimidinic endodeoxyribonuclease 2
- Gene ID
- 27301
- Gene Synonyms
- APE2; APEXL2; XTH2; ZGRF2
- ORF Size
- 1557 bp
- RefSeq#
- BC002959
- Gene Description
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).
- UniGene ID
- Hs.659558
- HGNC ID
- HGNC:17889
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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