human ANGPTL4 Adenovirus
This is an Adenovirus expressing Human ANGPTL4.
ADV-200919
Ad-h-ANGPTL4
Ready-to-use Adenovirus expressing Human ANGPTL4 (angiopoietin like 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171
Description (Vector)
ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. ANGPTL4 is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. ANGPTL4 was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
Gene ID
51129
Gene Name (Vector)
angiopoietin like 4
Gene Symbol
ANGPTL4
HGNC ID
HGNC:16039
ORF Size (aa)
1221
ORF Size (bp)
1221 bp
RefSeq ID
NM_139314
RefSeq Synonyms
NM_139314, NM_001039667, BC023647,
Species
human
UniGene ID
Hs.9613
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.