human AMACR Adenovirus

Name 
Ad-h-AMACR
Cat No 
ADV-200832
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ADCY3.

ADV-200832
Ad-h-AMACR

Ready-to-use Adenovirus expressing Human AMACR (alpha-methylacyl-CoA racemase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AMACRD; CBAS4; RACE; RM
Description (Vector)
AMACR encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Gene ID
23600
Gene Name (Vector)
alpha-methylacyl-CoA racemase
Gene Symbol
AMACR
HGNC ID
HGNC:451
ORF Size (aa)
597
ORF Size (bp)
597 bp
RefSeq ID
NM_014324
RefSeq Synonyms
NM_203382, NM_014324, NM_001167595, BC009471,
Species
human
UniGene ID
Hs.508343

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.