human ALDOB Adenovirus
This is an Adenovirus expressing Human ALDOB.
ADV-200759
Ad-h-ALDOB
Ready-to-use Adenovirus expressing Human ALDOB (aldolase, fructose-bisphosphate B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALDB; ALDO2
Description (Vector)
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
Gene ID
229
Gene Name (Vector)
aldolase, fructose-bisphosphate B
Gene Symbol
ALDOB
HGNC ID
HGNC:417
ORF Size (aa)
951
ORF Size (bp)
951 bp
RefSeq ID
NM_000035
RefSeq Synonyms
NM_000035, BC029399,
Species
human
UniGene ID
Hs.530274
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.