human ALDOA Adenovirus
This is an Adenovirus expressing Human ADAMTS5.
ADV-200753
Ad-h-ALDOA
Ready-to-use Adenovirus expressing Human ALDOA (aldolase, fructose-bisphosphate A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALDA; aldolase A, fructose-bisphosphate; epididymis secretory sperm binding protein Li 87p; fructose-1,6-bisphosphate triosephosphate-lyase; fructose-bisphosphate aldolase A; GSD12; HEL-S-87p; lung cancer antigen NY-LU-1; muscle-type aldolase
Description (eCommerce)
Aldolase A (fructose-bisphosphate aldolase) (ALDOA) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia [taken from NCBI Entrez Gene (Gene ID: 226)].
Description (Vector)
ALDOA, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
Gene ID
226
Gene Name (eCommerce)
aldolase, fructose-bisphosphate A
Gene Name (Vector)
aldolase, fructose-bisphosphate A
Gene Symbol
ALDOA
HGNC ID
HGNC:414
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1095
ORF Size (bp)
1095 bp
Protein Name (eCommerce)
Fructose-bisphosphate aldolase A
RefSeq ID
NM_000034
RefSeq Synonyms
NM_184043, NM_184041, NM_001243177, NM_001127617, NM_000034, BC016800, BC015888, BC013614, BC012880, BC010660, BC004333,
Research Areas
Breast Cancer,Cancer,Cytoskeleton,EGFR Signaling,HIF-1 Signaling,Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
cancer,cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
Aldolase A (fructose-bisphosphate aldolase) (ALDOA) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia [taken from NCBI Entrez Gene (Gene ID: 226)].
UniGene ID
Hs.513490
UniProt ID (eCommerce)
P04075
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.