human AKIRIN2 Adenovirus

Name 
Ad-h-AKIRIN2
Cat No 
ADV-200671
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AKIRIN2.

ADV-200671
Ad-h-AKIRIN2

Ready-to-use Adenovirus expressing Human AKIRIN2 (akirin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
akirin-2; C6orf166; dJ486L4.2; FBI1; fourteen-three-three beta interactant 1
Description (eCommerce)
Akirin2 is required for the innate immune response. It is a downstream effector of the Toll-like receptor (TLR), TNF, and IL-1 beta signaling pathways leading to the production of IL-6. Akirin-2 forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q53H80].
Gene ID
55122
Gene Name (eCommerce)
akirin 2
Gene Name (Vector)
akirin 2
Gene Symbol
AKIRIN2
HGNC ID
HGNC:21407
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
612
ORF Size (bp)
612 bp
Protein Name (eCommerce)
Akirin-2
RefSeq ID
NM_018064
RefSeq Synonyms
NM_018064, BC005051, BC003042, BC000764,
Research Areas
Immunology,Innate Immunity,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,transcription_translation
Species
human
Target Sentence
Akirin2 is required for the innate immune response. It is a downstream effector of the Toll-like receptor (TLR), TNF, and IL-1 beta signaling pathways leading to the production of IL-6. Akirin-2 forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q53H80].
UniGene ID
Hs.485915
UniProt ID (eCommerce)
Q53H80

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.