human AIPL1 Adenovirus

Name 
Ad-h-AIPL1
Cat No 
ADV-200630
Availability
4-5 weeks

This is an Adenovirus expressing Human ADAD1.

ADV-200630
Ad-h-AIPL1

Ready-to-use Adenovirus expressing Human AIPL1 (aryl hydrocarbon receptor interacting protein like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AIPL2; LCA4
Description (Vector)
Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA.
Gene ID
23746
Gene Name (Vector)
aryl hydrocarbon receptor interacting protein like 1
Gene Symbol
AIPL1
HGNC ID
HGNC:359
ORF Size (aa)
1155
ORF Size (bp)
1155 bp
RefSeq ID
NM_014336
RefSeq Synonyms
NM_014336, NM_001285403, NM_001285402, NM_001285401, NM_001285400, NM_001285399, NM_001033055, NM_001033054, BC012055,
Species
human
UniGene ID
Hs.279887

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.