human AFG3L2 Adenovirus

Name 
Ad-h-AFG3L2
Cat No 
ADV-200535
Availability
4-5 weeks

This is an Adenovirus expressing Human AFG3L2.

ADV-200535
Ad-h-AFG3L2

Ready-to-use Adenovirus expressing Human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AFG3 ATPase family gene 3-like 2; AFG3 ATPase family member 3-like 2; AFG3 like AAA ATPase 2; AFG3-like protein 2; ATPase family gene 3, yeast; paraplegin-like protein; SCA28; SPAX5
Description (eCommerce)
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. The gene encoding AFG3L2 is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders [taken from NCBI Entrez Gene (Gene ID: 10939)].
Description (Vector)
AFG3L2 encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
Gene ID
10939
Gene Name (eCommerce)
AFG3 like matrix AAA peptidase subunit 2
Gene Name (Vector)
AFG3 like matrix AAA peptidase subunit 2
Gene Symbol
AFG3L2
HGNC ID
HGNC:315
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2394
ORF Size (bp)
2394 bp
Protein Name (eCommerce)
AFG3-like protein 2
RefSeq ID
NM_006796
RefSeq Synonyms
NM_006796, BC065016,
Research Areas
Apoptosis,Axonogenesis,Mitochondrion,Neurobiology,Neurodegeneration,Neurodevelopment,Protein Folding
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology
Species
human
Target Sentence
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. The gene encoding AFG3L2 is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders [taken from NCBI Entrez Gene (Gene ID: 10939)].
UniGene ID
Hs.528996
UniProt ID (eCommerce)
Q9Y4W6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.