human ACTL7A Adenovirus

Name 
Ad-h-ACTL7A
Cat No 
ADV-200296
Availability
4-5 weeks

This is an Adenovirus expressing Human ACTL7A.

ADV-200296
Ad-h-ACTL7A

Ready-to-use Adenovirus expressing Human ACTL7A (actin like 7A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Gene ID
10881
Gene Name (Vector)
actin like 7A
Gene Symbol
ACTL7A
HGNC ID
HGNC:161
ORF Size (aa)
1308
ORF Size (bp)
1308 bp
RefSeq ID
NM_006687
RefSeq Synonyms
NM_006687, BC014610,
Species
human
UniGene ID
Hs.123530

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.