Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ACER2

Gene Name

alkaline ceramidase 2

Gene ID

340485

Gene Synonyms

ALKCDase2; ASAH3L

ORF Size

681 bp

RefSeq#

BC092487

Gene Description

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 (PubMed 16940153)).(supplied by OMIM, Jul 2010)

UniGene ID

Hs.41379

HGNC ID

HGNC:23675