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rat NOC2L Over-expression AAV

Name 
AAV-r-NOC2L
Cat No 
AAV-294202
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Noc2l.

AAV-294202
AAV-r-NOC2L

Ready-to-use AAV expressing Rat Noc2l (NOC2-like nucleolar associated transcriptional repressor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RGD1309387
Description (Vector)
Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.
Gene ID
313777
Gene Name (Vector)
NOC2-like nucleolar associated transcriptional repressor
Gene Symbol
Noc2l
ORF Size (aa)
1935
ORF Size (bp)
1935 bp
RefSeq ID
NM_001033897
RefSeq Synonyms
NM_001033897, BC101911,
Species
rat

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.