rat SKAP1 Over-expression AAV

Name
AAV-r-SKAP1

Cat No
AAV-293997

Availability
4-5 weeks

This is an AAV expressing Rat Skap1.

AAV-293997

AAV-r-SKAP1

Ready-to-use AAV expressing Rat Skap1 (src kinase associated phosphoprotein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Scap1; Skap55

Description (Vector)

Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.

Gene ID

286975

Gene Name (Vector)

src kinase associated phosphoprotein 1

Gene Symbol

Skap1

ORF Size (aa)

1065

ORF Size (bp)

1065 bp

RefSeq ID

NM_173311

RefSeq Synonyms

NM_173311, BC097931,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.