rat MTM1 Over-expression AAV
This is an AAV expressing Rat Mtm1.
AAV-293407
AAV-r-MTM1
Ready-to-use AAV expressing Rat Mtm1 (myotubularin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Gene ID
288762
Gene Name (Vector)
myotubularin 1
Gene Symbol
Mtm1
ORF Size (aa)
1662
ORF Size (bp)
1662 bp
RefSeq ID
NM_001013047
RefSeq Synonyms
NM_001013047, BC091225,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.