rat SGMS2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-292199
Availability:
3-5 weeks
Name:
AAV-r-SGMS2
This is an AAV expressing Rat Sgms2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Sgms2
- Gene Name
- sphingomyelin synthase 2
- Gene ID
- 310849
- Gene Synonyms
- RGD1305778; spermatin
- ORF Size
- 1098 bp
- RefSeq#
- BC085803
- Gene Description
- Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Required for cell growth.
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