rat NUAK2 Over-expression AAV
This is an AAV expressing Rat Nuak2.
AAV-292047
AAV-r-NUAK2
Ready-to-use AAV expressing Rat Nuak2 (NUAK family kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200013b22rik; Snark; UV126
Description (Vector)
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
Gene ID
289419
Gene Name (Vector)
NUAK family kinase 2
Gene Symbol
Nuak2
ORF Size (aa)
1893
ORF Size (bp)
1893 bp
RefSeq ID
NM_001007617
RefSeq Synonyms
NM_001007617, BC081899,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.