mouse NUAK2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-266164
Availability:
6-8 weeks
Name:
AAV-m-NUAK2-shRNA
This is an AAV expressing shRNA for silencing of Mouse Nuak2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Nuak2
- Gene Name
- NUAK family, SNF1-like kinase, 2
- Gene ID
- 74137
- Gene Synonyms
- 1200013B22Rik; mKIAA0537; Omphk2; Snark
- ORF Size
- 1896 bp
- RefSeq#
- NM_028778
- Gene Description
- Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
- UniGene ID
- Mm.100666
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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