rat ATF3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-290983
Availability:
3-5 weeks
Name:
AAV-r-ATF3
This is an AAV expressing Rat Atf3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Atf3
- Gene Name
- activating transcription factor 3
- Gene ID
- 25389
- Gene Synonyms
- LRF-1; LRFI
- ORF Size
- 546 bp
- RefSeq#
- BC078903
- Gene Description
- This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
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