mouse ASTL Over-expression AAV

Name 
AAV-m-ASTL
Cat No 
AAV-280557
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Astl.

AAV-280557
AAV-m-ASTL

Ready-to-use AAV expressing Mouse Astl (astacin-like metalloendopeptidase (M12 family)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
7420700F21; C87576; Sas1b
Description (Vector)
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).
Gene ID
215095
Gene Name (Vector)
astacin-like metalloendopeptidase (M12 family)
Gene Symbol
Astl
ORF Size (aa)
1308
ORF Size (bp)
1308 bp
RefSeq ID
NM_172539
RefSeq Synonyms
NM_172539, NM_001291003, BC064729,
Species
mouse
UniGene ID
Mm.31313

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.