mouse USP37 Over-expression AAV

Name 
AAV-m-USP37
Cat No 
AAV-277211
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Usp37.

AAV-277211
AAV-m-USP37

Ready-to-use AAV expressing Mouse Usp37 (ubiquitin specific peptidase 37). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4932415L06Rik; C330008N13Rik
Description (Vector)
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2).
Gene ID
319651
Gene Name (Vector)
ubiquitin specific peptidase 37
Gene Symbol
Usp37
ORF Size (aa)
2940
ORF Size (bp)
2940 bp
RefSeq ID
NM_176972
RefSeq Synonyms
NM_176972, NM_001310662, BC139091,
Species
mouse
UniGene ID
Mm.66568

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.