mouse USP37 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Usp37.
shADV-277211
Ad-m-USP37-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Usp37 (ubiquitin specific peptidase 37). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4932415L06Rik; C330008N13Rik
Description (Vector)
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2).
Gene ID
319651
Gene Name (Vector)
ubiquitin specific peptidase 37
Gene Symbol
Usp37
ORF Size (aa)
2940
ORF Size (bp)
2940 bp
RefSeq ID
NM_176972
RefSeq Synonyms
NM_176972, NM_001310662, BC139091,
Species
mouse
UniGene ID
Mm.66568
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.