mouse WDYHV1 Over-expression AAV

Name 
AAV-m-WDYHV1
Cat No 
AAV-276254
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Wdyhv1.

AAV-276254
AAV-m-WDYHV1

Ready-to-use AAV expressing Mouse Wdyhv1 (WDYHV motif containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2410187C16Rik; AU014961; AW550036; Ntaq1
Description (Vector)
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity).
Gene ID
76773
Gene Name (Vector)
WDYHV motif containing 1
Gene Symbol
Wdyhv1
ORF Size (aa)
630
RefSeq ID
NM_029734
RefSeq Synonyms
NM_029734, NM_001326602, NM_001326599, BC051524,
Species
mouse
UniGene ID
Mm.26771

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.