mouse VANGL2 Over-expression AAV

Name
AAV-m-VANGL2

Cat No
AAV-275961

Availability
4-5 weeks

This is an AAV expressing Mouse Vangl2.

AAV-275961

AAV-m-VANGL2

Ready-to-use AAV expressing Mouse Vangl2 (vang-like 2 (van gogh, Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C530001F03Rik; loop-tail; Lootl; Lp; Lpp1; Ltap; ska17; ska<m17Jus>; stbm; strabismus; Vang1l2

Description (Vector)

Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process (By similarity).

Gene ID

93840

Gene Name (Vector)

vang-like 2 (van gogh, Drosophila)

Gene Symbol

Vangl2

ORF Size (aa)

1566

ORF Size (bp)

1566 bp

RefSeq ID

NM_033509

RefSeq Synonyms

NM_033509, BC052195,

Species

mouse

UniGene ID

Mm.392110

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.