mouse UBE2V1 Over-expression AAV

Name 
AAV-m-UBE2V1
Cat No 
AAV-275503
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ube2v1.

AAV-275503
AAV-m-UBE2V1

Ready-to-use AAV expressing Mouse Ube2v1 (ubiquitin-conjugating enzyme E2 variant 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610011J09Rik; AI256840; CROC-1; CROC1; D7Bwg1382e; UEV-1
Description (Vector)
Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Gene ID
66589
Gene Name (Vector)
ubiquitin-conjugating enzyme E2 variant 1
Gene Symbol
Ube2v1
ORF Size (aa)
318
RefSeq ID
NM_023230
RefSeq Synonyms
NM_023230, NM_001311146, NM_001311131, BC092253, BC019372, BC003449,
Species
mouse
UniGene ID
Mm.360108

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.