mouse TWIST2 Over-expression AAV

Name
AAV-m-TWIST2

Cat No
AAV-275369

Availability
4-5 weeks

This is an AAV expressing Mouse Twist2.

AAV-275369

AAV-m-TWIST2

Ready-to-use AAV expressing Mouse Twist2 (twist basic helix-loop-helix transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bHLHa39; Dermo1

Description (Vector)

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Gene ID

13345

Gene Name (Vector)

twist basic helix-loop-helix transcription factor 2

Gene Symbol

Twist2

ORF Size (aa)

483

ORF Size (bp)

483 bp

RefSeq ID

NM_007855

RefSeq Synonyms

NM_007855, BC090636,

Species

mouse

UniGene ID

Mm.9474

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.