mouse TNFSF13B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-274725
Availability:
Immediate
Name:
AAV-m-TNFSF13B
This is an AAV expressing Mouse Tnfsf13b.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Tnfsf13b
- Gene Name
- tumor necrosis factor (ligand) superfamily, member 13b
- Gene ID
- 24099
- Gene Synonyms
- BAFF; BLyS; D8Ertd387e; TALL-1; TALL1; THANK; TNFSF20; Tnlg7a; zTNF4
- ORF Size
- 930 bp
- RefSeq#
- BC106841
- Gene Description
- Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response|Function: Isoform 2 seems to inhibit isoform 1 secretion and bioactivity (By similarity).
- UniGene ID
- Mm.28835
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