mouse TNFSF13B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tnfsf13b.
shAAV-274726
AAV-m-TNFSF13B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfsf13b (tumor necrosis factor (ligand) superfamily, member 13b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BAFF; BLyS; D8Ertd387e; TALL-1; TALL1; THANK; TNFSF20; Tnlg7a; zTNF4
Description (Vector)
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response|Function: Isoform 2 seems to inhibit isoform 1 secretion and bioactivity (By similarity).
Gene ID
24099
Gene Name (Vector)
tumor necrosis factor (ligand) superfamily, member 13b
Gene Symbol
Tnfsf13b
ORF Size (aa)
873
ORF Size (bp)
873 bp
RefSeq ID
NM_033622
RefSeq Synonyms
NM_033622, NM_001347309, BC106841, BC106840,
Species
mouse
UniGene ID
Mm.28835
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.