mouse TLR4 Over-expression AAV

Name 
AAV-m-TLR4
Cat No 
AAV-274280
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tlr4.

AAV-274280
AAV-m-TLR4

Ready-to-use AAV expressing Mouse Tlr4 (toll-like receptor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Lps; Ly87; Ran/M1; Rasl2-8
Description (Vector)
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.
Gene ID
21898
Gene Name (Vector)
toll-like receptor 4
Gene Symbol
Tlr4
ORF Size (aa)
2508
ORF Size (bp)
2508 bp
RefSeq ID
NM_021297
RefSeq Synonyms
NM_021297, BC029856,
Species
mouse
UniGene ID
Mm.38049

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.