mouse TLK1 Over-expression AAV

Name 
AAV-m-TLK1
Cat No 
AAV-274265
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tlk1.

AAV-274265
AAV-m-TLK1

Ready-to-use AAV expressing Mouse Tlk1 (tousled-like kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4930545J15Rik
Description (Vector)
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Gene ID
228012
Gene Name (Vector)
tousled-like kinase 1
Gene Symbol
Tlk1
ORF Size (aa)
2157
ORF Size (bp)
2157 bp
RefSeq ID
NM_172664
RefSeq Synonyms
NM_172664, BC051641,
Species
mouse
UniGene ID
Mm.136511

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.