mouse TLE4 Over-expression AAV

Name
AAV-m-TLE4

Cat No
AAV-274263

Availability
4-5 weeks

This is an AAV expressing Mouse Tle4.

AAV-274263

AAV-m-TLE4

Ready-to-use AAV expressing Mouse Tle4 (transducin-like enhancer of split 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

5730411M05Rik; AA792082; Bce-1; Bce1; ESTM13; ESTM14; grg-4; Grg4; X83332; X83333

Description (Vector)

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

Gene ID

21888

Gene Name (Vector)

transducin-like enhancer of split 4

Gene Symbol

Tle4

ORF Size (aa)

2322

ORF Size (bp)

2322 bp

RefSeq ID

NM_011600

RefSeq Synonyms

NM_011600, NM_001302951, NM_001302950, NM_001302947, BC165993,

Species

mouse

UniGene ID

Mm.103638

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.