mouse SOCS6 Over-expression AAV

Name 
AAV-m-SOCS6
Cat No 
AAV-272838
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Socs6.

AAV-272838
AAV-m-SOCS6

Ready-to-use AAV expressing Mouse Socs6 (suppressor of cytokine signaling 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1500012M23Rik; 5830401B18Rik; AI447482; Cis4; Cish4; HSPC060; SOCS-4; SOCS-6; Socs4; SSI4; STAI4; STATI4
Description (Vector)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Gene ID
54607
Gene Name (Vector)
suppressor of cytokine signaling 6
Gene Symbol
Socs6
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_018821
RefSeq Synonyms
NM_018821, BC094443, BC085245, BC017597,
Species
mouse
UniGene ID
Mm.414331

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.