mouse SOCS2 Over-expression AAV
This is an AAV expressing Mouse Socs2.
AAV-272832
AAV-m-SOCS2
Ready-to-use AAV expressing Mouse Socs2 (suppressor of cytokine signaling 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
8030460M17; AI527257; AW108012; CIS2; Cish2; D130043N08Rik; hg; JAB; SOCS-2; SSI-2
Description (Vector)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Gene ID
216233
Gene Name (Vector)
suppressor of cytokine signaling 2
Gene Symbol
Socs2
ORF Size (aa)
597
RefSeq ID
NM_007706
RefSeq Synonyms
NM_007706, NM_001168657, NM_001168656, NM_001168655, BC106153,
Species
mouse
UniGene ID
Mm.474283
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.