mouse SMYD2 Over-expression AAV

Name 
AAV-m-SMYD2
Cat No 
AAV-272692
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Smyd2.

AAV-272692
AAV-m-SMYD2

Ready-to-use AAV expressing Mouse Smyd2 (SET and MYND domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110020E07Rik; 4930402C15; KMT3C; Zmynd14
Description (Vector)
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
Gene ID
226830
Gene Name (Vector)
SET and MYND domain containing 2
Gene Symbol
Smyd2
ORF Size (aa)
1302
ORF Size (bp)
1302 bp
RefSeq ID
NM_026796
RefSeq Synonyms
NM_026796, BC023119,
Species
mouse
UniGene ID
Mm.156895

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.