mouse RECK Over-expression AAV

Name 
AAV-m-RECK
Cat No 
AAV-270359
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Reck.

AAV-270359
AAV-m-RECK

Ready-to-use AAV expressing Mouse Reck (reversion-inducing-cysteine-rich protein with kazal motifs). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mRECK; St15
Description (Vector)
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Gene ID
53614
Gene Name (Vector)
reversion-inducing-cysteine-rich protein with kazal motifs
Gene Symbol
Reck
ORF Size (aa)
2916
ORF Size (bp)
2916 bp
RefSeq ID
NM_016678
RefSeq Synonyms
NM_016678, BC138065, BC132197,
Species
mouse
UniGene ID
Mm.331573

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.